[{"@context":"https:\/\/schema.org\/","@type":"Article","@id":"https:\/\/www.neonevent.sk\/revolucia-v-transplantacii-organov\/#Article","mainEntityOfPage":"https:\/\/www.neonevent.sk\/revolucia-v-transplantacii-organov\/","headline":"Revol\u00facia v transplant\u00e1ci\u00ed org\u00e1nov","name":"Revol\u00facia v transplant\u00e1ci\u00ed org\u00e1nov","description":"Vedci vyu\u017e\u00edvaj\u00fa technol\u00f3giu na \u00fapravu g\u00e9nov a\u00a0na odstr\u00e1nenie v\u00edrusov u o\u0161\u00edpan\u00fdch, ktor\u00e9 by mohli by\u0165 \u0161kodliv\u00e9 pre \u013eud\u00ed, \u010do m\u00f4\u017ee. ","datePublished":"2017-06-28","dateModified":"2023-04-25","author":{"@type":"Person","@id":"https:\/\/www.neonevent.sk\/author\/#Person","name":"neonevent.sk\n","url":"https:\/\/www.neonevent.sk\/author\/","identifier":1,"image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/774cfd57496a9f02284489749b4229073861faca9d8a66df7d65507a77c5d31f?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/774cfd57496a9f02284489749b4229073861faca9d8a66df7d65507a77c5d31f?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"neonevent.sk","logo":{"@type":"ImageObject","@id":"\/logo.png","url":"\/logo.png","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/www.neonevent.sk\/wp-content\/uploads\/img_a282131_w2041_t1503940970.jpg","url":"https:\/\/www.neonevent.sk\/wp-content\/uploads\/img_a282131_w2041_t1503940970.jpg","height":0,"width":0},"url":"https:\/\/www.neonevent.sk\/revolucia-v-transplantacii-organov\/","about":["Technika"],"wordCount":391,"articleBody":"\tVedci vyu\u017e\u00edvaj\u00fa technol\u00f3giu na \u00fapravu g\u00e9nov a\u00a0na odstr\u00e1nenie v\u00edrusov u o\u0161\u00edpan\u00fdch, ktor\u00e9 by mohli by\u0165 \u0161kodliv\u00e9 pre \u013eud\u00ed, \u010do m\u00f4\u017ee predstavova\u0165 z\u00e1klad pre transplant\u00e1cie org\u00e1nov z o\u0161\u00edpan\u00fdch na \u010dloveka.\tV\u00fdskumn\u00edci z biotechnologickej firmy eGenesis pou\u017eili technol\u00f3giu na \u00fapravu g\u00e9nu CRISPR-Cas9 u o\u0161\u00edpan\u00fdch, ktor\u00fdm ch\u00fdba akt\u00edvny prasac\u00ed endog\u00e9nny retrov\u00edrus (PERV). CRISPR, ktor\u00fd bol porovnan\u00fd s p\u00e1rom „molekul\u00e1rnych no\u017en\u00edc“, umo\u017e\u0148uje vedcom zmeni\u0165 alebo nahradi\u0165 ur\u010dit\u00e9 \u010dasti DNA.\tCie\u013eom vedcov je zmierni\u0165 nedostatok dostupn\u00fdch org\u00e1nov na transplant\u00e1ciu \u013eud\u00ed.\tProfesorka genetiky na Harvardskej lek\u00e1rskej \u0161kole a poradky\u0148a eGenesis tvrd\u00ed, \u017ee teraz maj\u00fa \u017eiv\u00e9, zdrav\u00e9, \u0161tyri mesiace star\u00e9 o\u0161\u00edpan\u00e9, ktor\u00e9 boli otestovan\u00e9.\tMIT Technology Review uv\u00e1dza, \u017ee eGenesis doteraz vyrobila 37 prasiat zmenen\u00fdch g\u00e9nom. Asi 25 k\u00f3pi\u00ed v\u00edrusov bolo zni\u010den\u00fdch u embry\u00ed o\u0161\u00edpan\u00fdch, ktor\u00e9 boli implantovan\u00e9 do sami\u010d\u00edch o\u0161\u00edpan\u00fdch. O\u0161\u00edpan\u00e9 potom porodili prasiatka bez v\u00edrusu.\tS podobn\u00fdmi ve\u013ekos\u0165ami org\u00e1nov k \u013eu\u010fom vedci h\u013eadaj\u00fa sp\u00f4soby, ako pou\u017e\u00edva\u0165 zvierat\u00e1 na ve\u013ek\u00e9 mno\u017estvo org\u00e1nov\u00fdch transplant\u00e1tov. Prasacie org\u00e1ny s\u00fa v\u0161ak \u013eudsk\u00fdm telom r\u00fdchlo odmietnut\u00e9, a preto sa sna\u017eia, aby boli kompatibilnej\u0161ie.\tS\u00fa\u010dasne s odstra\u0148ovan\u00edm v\u00edrusov robia prasacie org\u00e1ny tak, aby ich \u013eudsk\u00fd pr\u00edjemca nezamietol. Nasleduj\u00faca etapa bude kombinova\u0165 tieto procesy a robi\u0165 klinick\u00e9 sk\u00fa\u0161ky.\tPod\u013ea odborn\u00edka na genetiku sa klinick\u00e9 \u0161t\u00fadie m\u00f4\u017eu vyskytn\u00fa\u0165 za dva roky.\tPod\u013ea eGenesis je toto hlavn\u00fd medzn\u00edk, skuto\u010dn\u00fd prielom v\u0161ak bude, ke\u010f sa \u013eudia bud\u00fa pohybova\u0165 po cel\u00e9 roky s org\u00e1nmi o\u0161\u00edpan\u00fdch, a\u017e potom budeme naozaj vedie\u0165, \u017ee je to bezpe\u010dn\u00e9 a \u00fa\u010dinn\u00e9.\tV \u010fal\u0161om projekte v\u00fdskumn\u00edci pou\u017eili g\u00e9nov\u00e9 \u00fapravy na korekciu g\u00e9novej mut\u00e1cie sp\u00f4sobuj\u00facej choroby v \u013eudsk\u00fdch embry\u00e1ch, \u010d\u00edm sa zabr\u00e1nilo prechodu mut\u00e1cie na bud\u00face gener\u00e1cie. V r\u00e1mci ohromuj\u00faceho objavu v\u00fdskumn\u00fd t\u00edm veden\u00fd Oregonskou zdravotn\u00edckou a vedeckou univerzitou uviedol, \u017ee embry\u00e1 sa dok\u00e1\u017eu napravi\u0165, ak sa vedci za\u010dn\u00fa skr\u00fdva\u0165.                                                                                                                                                                                                                                                                                                                                                                                        4.7\/5 - (4 votes)        "},{"@context":"https:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Revol\u00facia v transplant\u00e1ci\u00ed org\u00e1nov","item":"https:\/\/www.neonevent.sk\/revolucia-v-transplantacii-organov\/#breadcrumbitem"}]}]